Human cathelicidin peptide LL37 binds telomeric G-quadruplex.
نویسندگان
چکیده
Stabilization of G-quadruplex inhibits the activity of the enzyme telomerase in cancer cells. We found LL37, a host defense human cathelicidin antimicrobial peptide, to be a potent binder of G-quadruplex structures.
منابع مشابه
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عنوان ژورنال:
- Molecular bioSystems
دوره 9 7 شماره
صفحات -
تاریخ انتشار 2013